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Upon looking at the impact on the GST genotypes, only those with the null genotypes experienced a significant effect from taking NAC

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For example, a ferroptosis-prone chondrocyte cluster with high expression of ACSL4 and Tf, but low expression of FTH1 and TRPV1, has been identified in severely degenerated cartilage regions ( We propose that selectively targeting ferroptosis in specific cell populations may enhance therapeutic precision

Psychiatry 22 , 120126 (2016)